Azitromicina Versus Penicilina En Sifilis Temprana
Páginas: 38 (9314 palabras)
Publicado: 5 de enero de 2013
Azithromycin versus penicillin G benzathine for early syphilis (Review)
Bai ZG, Wang B, Yang K, Tian JH, Ma B, Liu Y, Jiang L, Gai QY, He X, Li Y
This is a reprint of a Cochrane review, prepared and maintained by The Cochrane Collaboration and published in The Cochrane Library 2012, Issue 6 http://www.thecochranelibrary.com
Azithromycin versus penicillin G benzathine for early syphilis(Review) Copyright © 2012 The Cochrane Collaboration. Published by John Wiley & Sons, Ltd.
TABLE OF CONTENTS HEADER . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . ABSTRACT . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . PLAIN LANGUAGE SUMMARY . . . . . . . . . . . . . . . . . . . . . . . . . . . . BACKGROUND . . . . . . . . . . . . . . . . . . .. . . . . . . . . . . . . . . OBJECTIVES . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . METHODS . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . RESULTS . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . Figure 1. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . Figure 2. . . . . . . . . . . . . . . . . . . .. . . . . . . . . . . . . . . . Figure 3. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . Figure 4. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . Figure 5. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . Figure 6. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . Figure 7. . . . . . . . . . . . . . . . . . . .. . . . . . . . . . . . . . . . DISCUSSION . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . AUTHORS’ CONCLUSIONS . . . . . . . . . . . . . . . . . . . . . . . . . . . . . ACKNOWLEDGEMENTS . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . REFERENCES . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . CHARACTERISTICS OF STUDIES . . . . . . . . . . .. . . . . . . . . . . . . . . . DATA AND ANALYSES . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . Analysis 1.1. Comparison 1 Cure rate, Outcome 1 Cure rate. . . . . . . . . . . . . . . . . . Analysis 1.2. Comparison 1 Cure rate, Outcome 2 Cumulative cure rate. . . . . . . . . . . . . . Analysis 2.1. Comparison 2 Subgroup analysis: syphilis stage, Outcome 1 Cure rate (syphilisstage). . . . . Analysis 3.1. Comparison 3 Subgroup analysis: dosage of azithromycin, Outcome 1 cure rate -different dosage. Analysis 4.1. Comparison 4 Adverse effects, Outcome 1 Adverse events. . . . . . . . . . . . . . . APPENDICES . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . HISTORY . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . CONTRIBUTIONS OFAUTHORS . . . . . . . . . . . . . . . . . . . . . . . . . . . DECLARATIONS OF INTEREST . . . . . . . . . . . . . . . . . . . . . . . . . . . . SOURCES OF SUPPORT . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . DIFFERENCES BETWEEN PROTOCOL AND REVIEW . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .. . . . . . . . . . . . 1 1 2 2 3 3 5 6 7 8 9 10 10 11 12 13 13 13 15 21 22 23 24 25 26 26 28 29 29 29 30
Azithromycin versus penicillin G benzathine for early syphilis (Review) Copyright © 2012 The Cochrane Collaboration. Published by John Wiley & Sons, Ltd.
i
[Intervention Review]
Azithromycin versus penicillin G benzathine for early syphilis
Zheng Gang Bai1 , Baoxi Wang2 , KeHuYang1 , Jin Hui Tian1 , Bin Ma1 , Yali Liu1 , Lei Jiang1 , Qiong Yan Gai3a , Xiaodong He4b , Youping Li5 Medicine Center, School of Basic Medical Sciences, Lanzhou University, Lanzhou City, China. 2 Institute of Dermatology, Chinese Academy of Medical Sciences, Nanjing, China. 3 Lanzhou University, Second Hospital, Lanzhou City, China. 4 The Second Clinical College of Lanzhou University, Lanzhou...
Bai ZG, Wang B, Yang K, Tian JH, Ma B, Liu Y, Jiang L, Gai QY, He X, Li Y
This is a reprint of a Cochrane review, prepared and maintained by The Cochrane Collaboration and published in The Cochrane Library 2012, Issue 6 http://www.thecochranelibrary.com
Azithromycin versus penicillin G benzathine for early syphilis(Review) Copyright © 2012 The Cochrane Collaboration. Published by John Wiley & Sons, Ltd.
TABLE OF CONTENTS HEADER . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . ABSTRACT . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . PLAIN LANGUAGE SUMMARY . . . . . . . . . . . . . . . . . . . . . . . . . . . . BACKGROUND . . . . . . . . . . . . . . . . . . .. . . . . . . . . . . . . . . OBJECTIVES . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . METHODS . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . RESULTS . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . Figure 1. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . Figure 2. . . . . . . . . . . . . . . . . . . .. . . . . . . . . . . . . . . . Figure 3. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . Figure 4. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . Figure 5. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . Figure 6. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . Figure 7. . . . . . . . . . . . . . . . . . . .. . . . . . . . . . . . . . . . DISCUSSION . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . AUTHORS’ CONCLUSIONS . . . . . . . . . . . . . . . . . . . . . . . . . . . . . ACKNOWLEDGEMENTS . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . REFERENCES . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . CHARACTERISTICS OF STUDIES . . . . . . . . . . .. . . . . . . . . . . . . . . . DATA AND ANALYSES . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . Analysis 1.1. Comparison 1 Cure rate, Outcome 1 Cure rate. . . . . . . . . . . . . . . . . . Analysis 1.2. Comparison 1 Cure rate, Outcome 2 Cumulative cure rate. . . . . . . . . . . . . . Analysis 2.1. Comparison 2 Subgroup analysis: syphilis stage, Outcome 1 Cure rate (syphilisstage). . . . . Analysis 3.1. Comparison 3 Subgroup analysis: dosage of azithromycin, Outcome 1 cure rate -different dosage. Analysis 4.1. Comparison 4 Adverse effects, Outcome 1 Adverse events. . . . . . . . . . . . . . . APPENDICES . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . HISTORY . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . CONTRIBUTIONS OFAUTHORS . . . . . . . . . . . . . . . . . . . . . . . . . . . DECLARATIONS OF INTEREST . . . . . . . . . . . . . . . . . . . . . . . . . . . . SOURCES OF SUPPORT . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . DIFFERENCES BETWEEN PROTOCOL AND REVIEW . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .. . . . . . . . . . . . 1 1 2 2 3 3 5 6 7 8 9 10 10 11 12 13 13 13 15 21 22 23 24 25 26 26 28 29 29 29 30
Azithromycin versus penicillin G benzathine for early syphilis (Review) Copyright © 2012 The Cochrane Collaboration. Published by John Wiley & Sons, Ltd.
i
[Intervention Review]
Azithromycin versus penicillin G benzathine for early syphilis
Zheng Gang Bai1 , Baoxi Wang2 , KeHuYang1 , Jin Hui Tian1 , Bin Ma1 , Yali Liu1 , Lei Jiang1 , Qiong Yan Gai3a , Xiaodong He4b , Youping Li5 Medicine Center, School of Basic Medical Sciences, Lanzhou University, Lanzhou City, China. 2 Institute of Dermatology, Chinese Academy of Medical Sciences, Nanjing, China. 3 Lanzhou University, Second Hospital, Lanzhou City, China. 4 The Second Clinical College of Lanzhou University, Lanzhou...
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