Breast Cancer Res Treat (2010) 121:413–419 DOI 10.1007/s10549-010-0913-0

CLINICAL TRIAL

Three versus six months of exercise training in breast cancer survivors
Lisa K. Sprod • City C. Hsieh •Reid Hayward Carole M. Schneider


Received: 27 January 2010 / Accepted: 21 April 2010 / Published online: 5 May 2010 Ó Springer Science+Business Media, LLC. 2010

Abstract Breast cancer is themost prevalent type of cancer in American women. Exercise appears to diminish many of the side effects resulting from breast cancer and its treatment. Very little research, however, has compared theoutcomes of varying lengths of combined aerobic and resistance training exercise interventions on physiological and psychological parameters in breast cancer survivors. The purpose of this study was tocompare the physiological and psychological outcomes following 3 and 6 months of exercise in breast cancer survivors. Breast cancer survivors (N = 114) participated in either 3 months ofprescriptive, individualized exercise (3M; n = 29), 6 months of prescriptive, individualized exercise (6M; n = 68), or served as sedentary controls (C; n = 17). Cancer survivors completed a medical evaluation andassessment at baseline followed by a predetermined 3- or 6-month exercise intervention. Cancer survivors in the control group performed no exercise between the initial assessment and 6-monthreassessment. Cardiovascular endurance, pulmonary function, muscular endurance, fatigue, and symptoms of depression were assessed at baseline and post intervention. Repeated measures ANCOVA revealedimprovements (P \ 0.05) in cardiovascular endurance, fatigue, and symptoms of depression in breast cancer survivors undergoing 3- and 6-month individualized exercise

interventions. Breast cancer survivorsexercising for 6 months showed additional improvements (P \ 0.05) in pulmonary function and muscular endurance. Cancer survivors in the control group did not improve in cardiovascular endurance,... [continua]

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