Fibrinolytic agent

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  • Publicado : 18 de enero de 2012
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(WO/2004/100879) METHOD AND COMPOSITION FOR PREVENTING OR REDUCING EDEMA, DEEP VEIN THROMBOSIS AND/OR PULMONARY EMBOLISM
WHAT IS CLAIMED IS: 1. A pharmaceutical preparation comprising effectiveamounts of a fibrinolytic agent and an antioxidant.
2. The composition of Claim 1, wherein the fibrinolytic agent is an enzyme selected from the group consisting of nattokinase, urokinase, subtilisin,and plasmin.
3. The composition of Claim 1, wherein the antioxidant is selected from the group consisting of : vitamin C, vitamin E, a catechin, a carotenoid, a flavonoid, coenzyme Q10 (ubiquinone), anisoflavone, a phenylpropanoid, a polyphenol, a tocopherol, alpha tocopherol, selenium, magnesium, a-lipoic acid, TBHQ, BHA, BHT, a tocotrienol, ascorbic acid, resveratrol, a pine bark extract, anoleoresin, rosemary extract, tea extract, grape seed extract, and an antioxidant extract from fruit skin or from a seed.
4. A pharmaceutical preparation comprising effective amounts of pine bark extractand nattokinase.
5. The pharmaceutical preparation of Claim 4, wherein said pine bark extract is prepared from French Maritime Pine, Pinus maritima.
6. A method for decreasing swelling of the lowerextremities, edema, pulmonary embolism, or thrombosis, comprising: administering a pharmaceutical preparation comprising a fibrinolytic agent and an antioxidant.
7. The method of Claim 6, whereinsaid swelling of the lower extremities, edema, pulmonary embolism, or thrombosis results from confinement or enforced inactivity.
8. The method of Claim 6, wherein said fibrinolytic agent is an enzyme.9. The method of Claim 8, wherein said enzyme is selected from the group consisting of urokinase, subtilisin, and plasmin.
10. The method of Claim 8, wherein said enzyme is nattokinase.
11. Themethod of Claim 6, wherein said antioxidant is selected from the group consisting of : vitamin C, vitamin E, a catechin, a carotenoid, a flavonoid, coenzyme Q10 (ubiquinone), an isoflavone, a...
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