Clinical pathological picture and prognostic factors for survival in adults with softttissue sarcoma.
DIAZ-PLASENCIA Juan*, SALAZAR RONCAL Jorge **, POMATANTA PLASENCIA Jorge **, TANTALEAN Enrique ***, GUZMAN Carlos *.
*Medico Asistente del Servicio de Cirugía Oncológica, HospitalBelén. Profesor Auxiliar de la Facultad de Medicina, Universidad Nacional de Trujillo. ** Medico Serumista. *** Jefe del Servicio de Cirugía Oncológica, Hospital Belén.
SUMMARY Objective: The mainobjective was to identify the clinico-pathologic-picture and the influence on prognosis of some variables. Material and methods: We analized retrospectively the files of 44 adults patients with soft-tissue sarcomas managed at Belen Hospital, Peru, between 1967 and 1994. Estimation of survival was made by the method of Kaplan - Meier and to assesss the prognostic variables we used the log-rank test.Results: The median age was 46± 19 years (range, 16 to 85 years) and there were 21 males and 23 females (M:F, 0.9:1). The most common complaints were tumor and pain. Twenty - three tumors (52%) werelocated in the lower and 9 (21%) in the upper extremities. Most patients were classified in UICC stage II (48%), followed by stage III (23%), stage IV (18%) and stage I (11%). The majority of tumorswere fibrosarcomas (34%), liposarcomas and rhabdomyosarcomas (14%). Thirteen tumors (30%) were classified as high - grade, 24 (55%) as intermediate - grade and 7 (16%) as low - grade. Twenty - sevenpatients underwent surgery, 13 received adjuvant chemotherapy and/or radiotherapy, and 4 were treated with primary chemotherapy and/or radiotherapy with 5 - year survival rates of 54%, 11 %, and 0%,respectively. The 5 - year survival rate for the entire group was 38%. According to an univariate analysis of the dependence of survival on variables, the following factors were significant: Age (p <...