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  • Publicado : 2 de diciembre de 2010
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Objective: describe the clinical characteristics and maternal perinatal complications of HELLP syndrome.
Design: Retrospective descriptive study.
Material and methods: Cases of HELLP syndrometreated at the Guillermo Almenara Irigoyen National Hospital(HNGAI) in 1999. Results: The incidence of HELLP syndrome was 16.3 per 1000 live births, 16 (41 percent) with full criteria and 23 (58.9percent) with partial HELLP.
It was recorded Stomachache and right upper quadrant pain in 46.2 percent of patients, associated with more thrombocytopenia (OR = 5, p <0.001). Major obstetriccomplications were disseminated intravascular coagulation 17 (43.6 percent), acute respiratory failure 14 (35.9 percent), premature detachment of placenta 9 (23.1) and eclampsia 4 (10.3 percent).
The partialHELLP complications were minor. Gestation was completed in 63 percent of patients between 33 and 37 weeks, 95 percent by caesarean section. Derivates Blood was used in 67 percent, according to theseverity of thrombocytopenia. Perinatal morbidity consisted of 28 (76 percent) premature and 19 (15 percent) newborn of low weight.
Maternal mortality was 0 percent and 14 percent perinatal latter isassociated with prematurity (OR = 10, p <0.005). In the development of thrombocytopenia was a maximum reduction during the first 48 hours after delivery, to a spontaneous platelet recovery after sevendays. Corticosteroids exert a beneficial effect on the advancement of this recovery.
Conclusion: HELLP syndrome is a condition of high maternal perinatal morbidity. Obstetric complications areassociated with more thrombocytopenia, while the perinatal to prematurity. The management medical surgical and intensive care support reduce complications associated with this entity. (AU)

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