Ciclo Urea

MCB 102 Fatty Acid Oxidation and Urea Production Worksheet: ANSWERS
1. Free fatty acids in the bloodstream are:
A) bound to hemoglobin.
B) carried by the protein serum albumin. *
C) freelysoluble in the aqueous phase of the blood.
D) nonexistent; the blood does not contain free fatty acids.
E) present at levels that are independent of epinephrine.
2. The role of hormone-sensitivetriacylglycerol lipase is to:
A) hydrolyze lipids stored in the liver.
B) hydrolyze membrane phospholipids in hormone-producing cells.
C) hydrolyze triacylglycerols stored in adipose tissue. *
D)synthesize lipids in adipose tissue.
E) synthesize triacylglycerols in the liver.
3.Transport of fatty acids from the cytoplasm to the mitochondrial matrix requires:
A) ATP, carnitine, and coenzyme A. *B) ATP, carnitine, and pyruvate dehydrogenase.
C) ATP, coenzyme A, and hexokinase.
D) ATP, coenzyme A, and pyruvate dehydrogenase.
E) carnitine, coenzyme A, and hexokinase.
4. What is the correctorder of function of the following enzymes of β oxidation?
1. β-Hydroxyacyl-CoA dehydrogenase
2. Thiolase
3. Enoyl-CoA hydratase
4. Acyl-CoA dehydrogenase
A) 4, 3, 1, 2 *
5. If the 16-carbonsaturated fatty acid palmitate is oxidized completely to carbon dioxide and
water (via the β-oxidation pathway and the citric acid cycle), and all of the energy-conserving
products are used to driveATP synthesis in the mitochondrion, the net yield of ATP per
molecule of palmitate is:
A) 3.
B) 10.
C) 25.
D) 108. *
E) 1,000.
6. Saturated fatty acids are degraded by the stepwise reactions ofβ oxidation, producing
acetyl-CoA. Under aerobic conditions, how many ATP molecules would be produced as a
consequence of removal of each acetyl-CoA?
4 *
7. Write a balanced equation for the βoxidation of palmitoyl-CoA, a 16-carbon, fully
saturated fatty acid, and indicate how much of each product is formed.
Ans: The overall reaction is:Palmitoyl-CoA + 7CoA-SH + 7FAD + 7NAD+ + 7H2O →
8...