Corrosion

METHOD VALIDATION AND QUALITY CONTROL PROCEDURES FOR PESTICIDE RESIDUES ANALYSIS IN FOOD AND FEED
Document No. SANCO/10684/2009

Supersedes Document No. SANCO/3131/2007 Implemented by 01/01/2010
Coordinator Dr. Tuija Pihlström National Food Administration, Uppsala, Sweden.

Advisory Group Dr. Michelangelo Anastassiades Mr. Arne Andersson Dr. André de Kok CVUA Stuttgart, Germany.Fellbach,

National Food Administration, Uppsala, Sweden. Food and Consumer Product Safety Authority (VWA), Amsterdam, The Netherlands. Danish Institute for Food and Veterinary Research, Soeborg, Denmark. University of Almería, Spain. Generalitat Valenciana, Spain. CVUA Freiburg, Germany. University of Almería, Spain. University of Almería, Spain. AGES GmbH, Competence Center for Residuesof Plant Protection Products, Innsbruck, Austria. RIKILT - Institute of Food Safety, Wageningen, The Netherlands. Central Science Laboratory, York, United Kingdom. University of Almería, Spain. Legal Deposit: AL-1133-2009

Dr. Mette Erecius Poulsen

Dr. Amadeo R. Fernández-Alba Dr. Miguel Gamón Dr. Ralf Lippold Mr. Octavio Malato Ms. Paula Medina Dr. Sonja Masselter (AG)

Dr. HansMol, Senior Chemist (AG) Mr. Stewart Reynolds Dr. Antonio Valverde

TABLE OF CONTENTS
Introduction .............................................................................................................................. 3 Accreditation and legal background................................................................................... 3 Sampling, transport, processing andstorage of samples .................................................. 4 Sampling ......................................................................................................................................4 Laboratory sample transportation ...........................................................................................4 Sample preparation and processing prior toanalysis ..........................................................4 Pesticide standards, calibration solutions, etc..................................................................... 5 Identity, purity, and storage of standards...............................................................................5 Preparation and storage of stock standards.........................................................................5 Preparation, use and storage of working standards.............................................................6 Testing and replacement of standards...................................................................................6 Extraction and concentration ................................................................................................ 6Extraction conditions and efficiency.......................................................................................6 Extract concentration and dilution to volume.......................................................................7 Contamination and interference ........................................................................................... 7Contamination............................................................................................................................7 Interference.................................................................................................................................7 Analytical calibration, representative analytes, matrix effects and chromatographic integration................................................................................................................................ 8 General requirements................................................................................................................8 Calibration ...................................................................................................................................8 Representative...