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Polymeric Drug Delivery Systems

DRUGS AND THE PHARMACEUTICAL SCIENCES
Executive Editor

James Swarbrick
PharmaceuTech, Inc. Pinehurst, North Carolina

Advisory Board
Larry L. Augsburger
University of Maryland Baltimore, Maryland

Harry G. Brittain
Center for Pharmaceutical Physics Milford, New Jersey

Jennifer B. Dressman
Johann Wolfgang Goethe University Frankfurt, GermanyAnthony J. Hickey
University of North Carolina School of Pharmacy Chapel Hill, North Carolina

Jeffrey A. Hughes
University of Florida College of Pharmacy Gainesville, Florida

Ajaz Hussain
U.S. Food and Drug Administration Frederick, Maryland

Trevor M. Jones
The Association of the British Pharmaceutical Industry London, United Kingdom

Hans E. Junginger
Leiden/Amsterdam Center forDrug Research Leiden, The Netherlands

Vincent H. L. Lee
University of Southern California Los Angeles, California

Stephen G. Schulman
University of Florida Gainesville, Florida

Jerome P. Skelly
Alexandria, Virginia

Elizabeth M. Topp
University of Kansas School of Pharmacy Lawrence, Kansas

Geoffrey T. Tucker
University of Sheffield Royal Hallamshire Hospital Sheffield, UnitedKingdom

Peter York
University of Bradford School of Pharmacy Bradford, United Kingdom

DRUGS AND THE PHARMACEUTICAL SCIENCES
A Series of Textbooks and Monographs

1. Pharmacokinetics, Milo Gibaldi and Donald Perrier 2. Good Manufacturing Practices for Pharmaceuticals: A Plan for Total Quality Control, Sidney H. Willig, Murray M. Tuckerman, and William S. Hitchings IV 3. Microencapsulation,edited by J. R. Nixon 4. Drug Metabolism: Chemical and Biochemical Aspects, Bernard Testa and Peter Jenner 5. New Drugs: Discovery and Development, edited by Alan A. Rubin 6. Sustained and Controlled Release Drug Delivery Systems, edited by Joseph R. Robinson 7. Modern Pharmaceutics, edited by Gilbert S. Banker and Christopher T. Rhodes 8. Prescription Drugs in Short Supply: Case Histories,Michael A. Schwartz 9. Activated Charcoal: Antidotal and Other Medical Uses, David O. Cooney 10. Concepts in Drug Metabolism (in two parts), edited by Peter Jenner and Bernard Testa 11. Pharmaceutical Analysis: Modern Methods (in two parts), edited by James W. Munson 12. Techniques of Solubilization of Drugs, edited by Samuel H. Yalkowsky 13. Orphan Drugs, edited by Fred E. Karch 14. Novel Drug DeliverySystems: Fundamentals, Developmental Concepts, Biomedical Assessments, Yie W. Chien 15. Pharmacokinetics: Second Edition, Revised and Expanded, Milo Gibaldi and Donald Perrier 16. Good Manufacturing Practices for Pharmaceuticals: A Plan for Total Quality Control, Second Edition, Revised and Expanded, Sidney H. Willig, Murray M. Tuckerman, and William S. Hitchings IV 17. Formulation of VeterinaryDosage Forms, edited by Jack Blodinger 18. Dermatological Formulations: Percutaneous Absorption, Brian W. Barry 19. The Clinical Research Process in the Pharmaceutical Industry, edited by Gary M. Matoren 20. Microencapsulation and Related Drug Processes, Patrick B. Deasy 21. Drugs and Nutrients: The Interactive Effects, edited by Daphne A. Roe and T. Colin Campbell 22. Biotechnology of IndustrialAntibiotics, Erick J. Vandamme 23. Pharmaceutical Process Validation, edited by Bernard T. Loftus and Robert A. Nash

24. Anticancer and Interferon Agents: Synthesis and Properties, edited by Raphael M. Ottenbrite and George B. Butler 25. Pharmaceutical Statistics: Practical and Clinical Applications, Sanford Bolton 26. Drug Dynamics for Analytical, Clinical, and Biological Chemists, BenjaminJ. Gudzinowicz, Burrows T. Younkin, Jr., and Michael J. Gudzinowicz 27. Modern Analysis of Antibiotics, edited by Adjoran Aszalos 28. Solubility and Related Properties, Kenneth C. James 29. Controlled Drug Delivery: Fundamentals and Applications, Second Edition, Revised and Expanded, edited by Joseph R. Robinson and Vincent H. Lee 30. New Drug Approval Process: Clinical and Regulatory Management,...