Embriologia

Embryology of the Eye and Visual Pathways— Anatomy and General Organization
Patrick O’Connor, Ph.D.
Department of Biomedical Sciences Ohio University College of Osteopathic Medicine Athens, Ohio45701 oconnorp@ohiou.edu
http://www.eb.tuebingen.mpg.de/eye-screen/

OUTLINE—Wednesday April 16, 2003
Embryology of the eye Extraocular muscles Visual reflexes Pupillary Light Reflex Near ReflexIris Cornea Ciliary Body

Retinal Layer Fibrous Layer Uveal Layer (neural)
Retina Choroid Sclera

Modified from Netter, 1989

Vitreous Body

CHAMBERS
Modified from Netter, 19891—Anterior Chamber 2—Posterior Chamber

“Aqueous Chamber”

CHAMBERS
Modified from Netter, 1989

Hyaloid Canal

Central Vessels of Retina

Modified from Netter, 1989

Development of the Eye
I.First noticeable ~ 22days
optic grooves—developing neural tube

Moore and Persaud, 1998

Development of the Eye
II. As neural folds fuse (= forebrain formation)
optic vesicles—evaginations offorebrain

Moore and Persaud, 1998

Development of the Eye
IIIa. Induction of lens placode (surface ectoderm) IIIb. Formation of optic stalk and optic cup from optic vesicle

Moore andPersaud, 1998

Continued development of optic cup and lens
Optic cup — invagination of distal optic vesicle to form doublewalled “cup” Optic (choroid) fissure —sulcus on ventral aspect optic cup/stalk(allows passage of vasculature to lens & layers of cup) Lens placode — ectodermal thickening Lens pit— invaginates to form lens vesicle
Moore and Persaud, 1998

Moore and Persaud, 1998Development of the retina outer & inner portions of the optic cup Closure of choroid fissure ~ 6-7 weeks

Optic Cup

Inner layer — neuroepithelium “neural retina”

Outer layer— retinal pigment epitheliumIntraretinal space

Moore and Persaud, 1998

Cavity of optic stalk “filled” with axons of optic nerve

“Fusion” of inner and outer portions of the optic cup

Moore and Persaud, 1998...