Renal
Páginas: 2 (386 palabras)
Publicado: 9 de diciembre de 2012
Original Research
Chronic Kidney Disease and Associated Risk Factors in the Bajo Lempa Region of El Salvador: Nefrolempa Study, 2009
Carlos M. Orantes MD, Raúl Herrera MD PhD DrSc, MiguelAlmaguer MD, Elsy G. Brizuela MD, Carlos E. Hernández MD, Héctor Bayarre MD PhD, Juan C. Amaya MD, Denis J. Calero MD, Patricia Orellana, Rosa M. Colindres RN, María E. Velázquez, Sonia G. Núñez, VerónicaMabel Contreras, Bertha E. Castro
ABSTRACT
INTRODUCTION In El Salvador, end-stage renal disease is the leading cause of hospital deaths in adults, the second cause of death in men and the ¿fthleading cause of death in adults of both sexes in the general population. OBJECTIVE Identify risk factors for chronic kidney disease and urinary markers of renal and vascular damage, measure kidneyfunction and characterize prevalence of chronic kidney disease in persons aged 18 years in the Bajo Lempa region of El Salvador. METHODS A cross-sectional analytical epidemiological study was carriedout using active screening for chronic kidney disease and associated risk factors in individuals aged 18 years in the Bajo Lempa Region, a rural, coastal area in El Salvador. Door-to-door visits andclinical examinations were conducted. Epidemiological and clinical data were collected including: family and personal clinical history of disease; biological, behavioral, social and environmentalrisk factors; physical measurements; urinalysis for markers of renal and vascular damage; and blood tests (serum creatinine, serum glucose, lipid pro¿le). Glomerular ¿ltration rate was calculated usingthe Modi¿cation of Diet in Renal Disease formula. Chronic kidney disease case con¿rmation was done three months later. Multiple logistic regression was used for data analysis. RESULTS A total of 375families and 775 individuals (343 men, 432 women) were studied—88.3% of the total resident population in the region. Elevated prevalence of risk factors was observed: diabetes mellitus, 10.3%;...
Chronic Kidney Disease and Associated Risk Factors in the Bajo Lempa Region of El Salvador: Nefrolempa Study, 2009
Carlos M. Orantes MD, Raúl Herrera MD PhD DrSc, MiguelAlmaguer MD, Elsy G. Brizuela MD, Carlos E. Hernández MD, Héctor Bayarre MD PhD, Juan C. Amaya MD, Denis J. Calero MD, Patricia Orellana, Rosa M. Colindres RN, María E. Velázquez, Sonia G. Núñez, VerónicaMabel Contreras, Bertha E. Castro
ABSTRACT
INTRODUCTION In El Salvador, end-stage renal disease is the leading cause of hospital deaths in adults, the second cause of death in men and the ¿fthleading cause of death in adults of both sexes in the general population. OBJECTIVE Identify risk factors for chronic kidney disease and urinary markers of renal and vascular damage, measure kidneyfunction and characterize prevalence of chronic kidney disease in persons aged 18 years in the Bajo Lempa region of El Salvador. METHODS A cross-sectional analytical epidemiological study was carriedout using active screening for chronic kidney disease and associated risk factors in individuals aged 18 years in the Bajo Lempa Region, a rural, coastal area in El Salvador. Door-to-door visits andclinical examinations were conducted. Epidemiological and clinical data were collected including: family and personal clinical history of disease; biological, behavioral, social and environmentalrisk factors; physical measurements; urinalysis for markers of renal and vascular damage; and blood tests (serum creatinine, serum glucose, lipid pro¿le). Glomerular ¿ltration rate was calculated usingthe Modi¿cation of Diet in Renal Disease formula. Chronic kidney disease case con¿rmation was done three months later. Multiple logistic regression was used for data analysis. RESULTS A total of 375families and 775 individuals (343 men, 432 women) were studied—88.3% of the total resident population in the region. Elevated prevalence of risk factors was observed: diabetes mellitus, 10.3%;...
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