Rhabdomyosarcoma (RMS or "rhabdo") is a cancerous tumor that develops in the body's soft tissues, usually the muscles. It can affect the head, neck, bladder, vagina, arms, legs, and trunk.Cells from these tumors are often fast growing and can spread (metastasize) to other parts of the body.
RMS is the most common type of soft-tissue cancer in children. Kids can develop it at any age,but it's most common in those between 2 and 6 years old and 15 and 19 years old. Boys tend to be affected more often than girls.
Treatment of RMS includes chemotherapy, surgery, or radiation. Withearly detection and timely treatment, most kids make a full recovery.
Types of Tumors
The two main types of RMS in kids are:
1. Embryonal RMS: This tumor develops in the head and neck area,genitals, or urinary tract. It usually occurs in kids younger than 6. Although it's considered an aggressive (fast growing) type of tumor, it usually responds well to treatment.
2. Alveolar RMS: Thistype, which is most likely to occur during the teen years, most often affects the arms or legs, chest, abdomen, genitals, or anal areas. It, too, is fast growing but often more difficult to treat. Mostkids with this type of tumor need intensive treatment.
The cause of RMS is still unclear, but many researchers believe the tumor may begin to develop before birth. It's likely that, in adeveloping fetus, a genetic mutation or error occurs inside the cells, causing them to eventually develop into muscle tissue. In some kids, this may later lead to the disease.
Doctors also know thatcertain medical conditions can make some children more likely to develop rhabdomyosarcoma. These include genetic conditions such as:
* Li-Fraumeni syndrome, a disorder that predisposes kids tocertain types of cancer
* neurofibromatosis, a condition that causes tumors to grow on nerve tissue
* Beckwith-Wiedemann syndrome, a disorder that causes excessive growth
* Costello syndrome...
Leer documento completo
Regístrate para leer el documento completo.