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Atopic dermatitis (AD, a type of eczema) is an inflammatory, chronically relapsing, non-contagious and pruritic skin disorder.[1] It has been given names like "prurigo Besnier," "neurodermitis," "endogenous eczema," "flexural eczema," "infantile eczema," and "prurigo diathésique".[2]
Contents  [hide]  * 1 Signs and symptoms * 2 Causes * 2.1 Epidermal Barrier Dysfunction *2.2 Allergy * 2.3 Microwave radiation * 2.4 Food allergy * 2.5 Histamine intolerance * 2.6 Biological * 3 Prevention * 3.1 Diet * 3.2 Environment and lifestyle * 3.3 Allergen/irritant evasion * 4 Treatment * 4.1 Maintaining the skin barrier * 4.2 Prescription drugs * 4.3 Light (UV) therapy * 4.4 Alternative treatments * 4.5 Future research *5 Epidemiology * 6 See also * 7 References * 8 External links |
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[edit]Signs and symptoms

Atopic dermatitis of the anterior flextural crease of the elbow.

Pattern of atopic eczema varies with age
The skin of a patient with atopic dermatitis reacts abnormally and easily to irritants, food, and environmental allergens and becomes red,flaky and very itchy. It also becomes vulnerable to surface infections caused by bacteria. The skin on the flexural surfaces of the joints (for example inner sides of elbows and knees) are the most commonly affected regions in people.
Atopic dermatitis often occurs together with other atopic diseases like hay fever, asthma and allergic conjunctivitis. It is a familial and chronic disease and itssymptoms can increase or disappear over time. Atopic dermatitis in older children and adults is often confused with psoriasis. Atopic dermatitis afflicts humans, particularly young children; it is also a well-characterized disease in domestic dogs.
Although there is no cure for atopic eczema, and its cause is not well understood, it can be treated very effectively in the short term through acombination of prevention (learning what triggers the allergic reactions) and drug therapy.
Atopic dermatitis most often begins in childhood before age 5 and may persist into adulthood. For some, it flares periodically and then subsides for a time, even up to several years.[3] Yet, it is estimated that 75% of the cases of atopic dermatitis improve by the time children reach adolescence, whereas 25%continue to have difficulties with the condition through adulthood.[4]
Although atopic dermatitis can theoretically affect any part of the body, it tends to be more frequent on the hands and feet, on the ankles, wrists, face, neckand upper chest. Atopic dermatitis can also affect the skin around the eyes, including the eyelids.[5]
In most patients, the usual symptoms that occur with this type ofdermatitis are aggravated by a Staphylococcus aureus infection, dry skin, stress, lowhumidity and sweating, dust or sand or cigarette smoke. Also, the condition can be worsened by having long and hot baths or showers, solvents, cleaners ordetergents and wool fabrics or clothing.
Atopic dermatitis is also known as infantile eczema, when it occurs in infants. Infantile eczema may continue intochildhood and adolescence and it often involves an oozing, crusting rash mainly on the scalp and face, although it can occur anywhere on the body.[6] The appearance of the rash tends to modify, becoming dryer in childhood and then scaly or thickened in adolescence while the itching is persistent.
Approximately 50% of the patients who develop the condition display symptoms before the age of 1, and 80%display symptoms within the first 5 years of life.[4]
Symptoms may vary from person to person but they are usually present as a red, inflamed, and itchy rash and can quickly develop into raised and painful bumps.[7] The first sign of atopic dermatitis is the red to brownish-gray colored patches that are usually very itchy. Itching may become more intense during the night. The skin may present...