Tabebuia

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Natural Product Research
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Quinones from plants of northeastern Brazil: structural diversity, chemical transformations, NMR data and biological activities
Telma L. G. Lemos , Francisco J. Q. Monte , Allana Kellen L. Santos , Aluisio M. Fonseca , Héélcio S. Santos , Mailcar F. Oliveira , Sonia M. O. Costa , Otilia D. L. Pessoa & Raimundo Braz-Filho
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Departamento de Quíímica Orgâânicae Inorgâânica, Universidade Federal do Cearáá, Campus do Pici, CEP-60451-970 Fortaleza, Cearáá, Brazil
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Setor de Quíímica de Produtos Naturais, Universidade Estadual do Norte Fluminense Darcy Ribeiro, 28013-600, Campos dos Goytacazes, Rio de Janeiro, Brazil Available online: 11 May 2007

To cite this article: Telma L. G. Lemos, Francisco J. Q. Monte, Allana Kellen L. Santos, Aluisio M.Fonseca, Héélcio S. Santos, Mailcar F. Oliveira, Sonia M. O. Costa, Otilia D. L. Pessoa & Raimundo Braz-Filho (2007): Quinones from plants of northeastern Brazil: structural diversity, chemical transformations, NMR data and biological activities, Natural Product Research, 21:6, 529-550 To link to this article: http://dx.doi.org/10.1080/14786410601130604

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Natural Product Research, Vol. 21, No. 6, 20 May 2007, 529–550

Quinones from plants of northeastern Brazil: structural diversity, chemical transformations, NMR data and biological activities
Downloaded by [Cinvestav del IPN] at 10:07 09 September 2011
TELMA L. G. LEMOS*y, FRANCISCO J. Q. MONTEy, ALLANAKELLEN ´ L. SANTOSy, ALUISIO M. FONSECAy, HELCIO S. SANTOSy, MAILCAR F. OLIVEIRAy, SONIA M. O. COSTAy, OTILIA D. L. PESSOAy and RAIMUNDO BRAZ-FILHOz
´ yDepartamento de Quı´ mica Organica e Inorganica, Universidade Federal do Ceara, ˆ ˆ ´ Campus do Pici, CEP-60451-970 Fortaleza, Ceara, Brazil zSetor de Quı´ mica de Produtos Naturais, Universidade Estadual do Norte Fluminense Darcy Ribeiro, 28013-600,Campos dos Goytacazes, Rio de Janeiro, Brazil
(Received 15 January 2007; in final form 15 February 2007) The present review focus in quinones found in species of Brazilian northeastern Capraria biflora, Lippia sidoides, Lippia microphylla and Tabebuia serratifolia. The review cover ethnopharmacological aspects including photography of species, chemical structure feature, NMR datea and biologicalproperties. Chemical transformations of lapachol to form enamine derivatives and biological activities are discussed. Keywords: Capraria biflora; Lippia sidoides; Lippia microphylla; Tabebuia serratifolia; NMR data; Biological activities; Chemical reaction

1. Introduction Quinones are interesting natural products, widespread in nature, being found in plants, fungi, bacteria, and also in the...