Tratamiento Dental

Latest Research on Treatment of Dental Pain
Evaluation of ibuprofen/paracetamol for postoperative dental pain PAIN-Volume 152, Issue 3 , Pages 632-642, March 2011.
Subjects with at least 3 impacted third molars and experiencing moderate to severe postoperative pain were randomised to receive: 1 or 2 tablets of a single-tablet combination of ibuprofen 200mg/paracetamol 500mg; 2 tablets ofibuprofen 200 mg/codeine 12.8mg; 2 tablets of paracetamol 500mg/codeine 15mg; or placebo. Results for the primary endpoint, the sum of the mean scores of pain relief combined with pain intensity differences over 12hours, demonstrated that 1 and 2 tablets of the single-tablet combination of ibuprofen/paracetamol were statistically significantly more efficacious than 2 tablets of placebo (P<0.0001) andparacetamol/codeine (P?0.0001); furthermore, 2 tablets offered significantly superior pain relief to ibuprofen/codeine (P=0.0001), and 1 tablet was found noninferior to this combination. Adverse events were uncommon during this study and treatment emergent adverse events were statistically significantly less frequent in the groups taking the ibuprofen/paracetamol combination compared with codeinecombinations. In conclusion, 1 or 2 tablets of a single-tablet combination of ibuprofen 200mg/paracetamol 500mg provided highly effective analgesia that was comparable with, or superior to, other combination analgesics currently indicated for strong pain..
Does Dental Pain Improve With Oral Prednisone?Annals of Emergency Medicine, Volume 56, Issue 3, Supplement , Page S141, September 2010Patients were then asked to rate their pain on a visual analog scale of 1-10 (VAS, with 10 being the worst) at presentation. In the ED, subjects were given either 60 mg of prednisone or a placebo and discharged with acetaminophen/hydrocodone, Pen VK or Clindamycin if penicillin-allergic, and 2 pills of either a placebo or 60 mg prednisone. Patients were called at 24 and 48 hours and again asked to ratetheir pain The administration of a 3-day burst of prednisone to patients with pulpitis did not result in a statistically significant reduction in pain at either 24 or 48 hours compared to placebo. The administration of prednisone also did not cause a significant reduction in the amount of narcotics taken, or the patients' overall improvement. Therefore, this study suggests that the addition ofprednisone to for the treatment of pulpitis does not significantly reduce pain or decrease narcotic use.
Paracetamol for pain relief after surgical removal of lower wisdom teeth. Cochrane Database of Systematic Reviews 2007, Issue 3
Twenty-one trials (with over 2000 participants) were included. Paracetamol provided a statistically significant benefit when compared with placebo for pain relief atboth 4 and 6 hours after taking the drug. It is most effective at 1000 mg dose, and can be taken at six hourly intervals without compromising safety. There was no statistically significant difference between the number of patients who reported adverse events, overall this being 19% in the paracetamol group and 16% in the placebo group. It should be noted that most of the studies were found to havesome limitations mainly due to poor reporting of information. However the review concludes that paracetamol is a safe, effective drug for the treatment of postoperative pain following the surgical removal of lower wisdom teeth. FULL REVIEW

1. Moller, P.L., et al., Time to onset of analgesia and analgesic efficacy of effervescent acetaminophen 1000 mg compared to tablet acetaminophen 1000 mg inpostoperative dental pain: a single-dose, double-blind, randomized, placebo-controlled study [In Process Citation]. J Clin Pharmacol, 2000. 40(4): p. 370-8.
This randomized, double-blind, placebo-controlled study compared the time to onset of analgesia and the analgesic efficacy of two formulations of acetaminophen 1000 mg--an effervescent solution and tablet--in 242 patients with moderate or...