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Generic antibiotics, antibiotic resistance, and drug licensing
See Newsdesk page 746

International concerns that continue to voice the increasing problem of drug-resistantpathogens and the dearth of new and effective antibiotics are again emphasised by Kumarasamy and colleagues’ Article.1

Although new drugs continue to be licensed, too few are based on novel chemicalentities; drug resistance is more likely to occur when new agents are variants of existing classes. There is a serious mismatch between clinical need and supply of new medicines for which there is no...