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Páginas: 3 (558 palabras) Publicado: 29 de julio de 2012
Exp Clin Psychopharmacol. 2012 Jun 25. [Epub ahead of print]
Residual Effects of Cannabis Use on Neurocognitive Performance After Prolonged Abstinence: A Meta-Analysis.
Schreiner AM, Dunn ME.Abstract
Cannabis is the most widely used illicit drug in the U.S., and the number of illicit and licit users is rising. Lasting neurocognitive changes or deficits as a result of use are frequently noteddespite a lack of clarity in the scientific literature. In an effort to resolve inconsistencies in the evidence of lasting residual effects of cannabis use, we conducted two meta-analyses. First, weupdated a previous meta-analysis on broad nonacute cognitive effects of cannabis use through inclusion of newer studies. In a second meta-analysis, we focused on evidence for lasting residual effectsby including only studies that tested users after at least 25 days of abstinence. In the first meta-analysis, 33 studies met inclusion criteria. Results indicated a small negative effect for globalneurocognitive performance as well for most cognitive domains assessed. Unfortunately, methodological limitations of these studies prevented the exclusion of withdrawal symptoms as an explanation forobserved effects. In the second meta-analysis, 13 of the original 33 studies met inclusion criteria. Results indicated no significant effect of cannabis use on global neurocognitive performance or anyeffect on the eight assessed domains. Overall, these meta-analyses demonstrate that any negative residual effects on neurocognitive performance attributable to either cannabis residue or withdrawalsymptoms are limited to the first 25 days of abstinence. Furthermore, there was no evidence for enduring negative effects of cannabis use. (PsycINFO Database Record (c) 2012 APA, all rightsreserved).[PubMed - as supplied by publisher]
El cannabis es la droga ilícita más ampliamente utilizada en los EE.UU., y el número de usuarios legales e ilegales va en aumento. Cambios duraderos o déficits...
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