Vago

Nebulized hypertonic saline solution for acute bronchiolitis in
infants (Review)
Zhang L, Mendoza-Sassi RA, Wainwright C, Klassen TP

This is a reprint of a Cochrane review, prepared and maintained by The Cochrane Collaboration and published in The Cochrane Library
2011, Issue 3
http://www.thecochranelibrary.com

Nebulized hypertonic saline solution for acute bronchiolitis in infants(Review)
Copyright © 2011 The Cochrane Collaboration. Published by John Wiley & Sons, Ltd.

TABLE OF CONTENTS
HEADER . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
ABSTRACT . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
PLAIN LANGUAGE SUMMARY . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
BACKGROUND . . . . . . . . . . .. . . . . . . . . . . . . . . . . . . . . . . . .
OBJECTIVES . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
METHODS . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
RESULTS . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
Figure 1.
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Figure 2......................................
Figure 3.
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Figure 4.
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Figure 5.
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Figure 6.
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DISCUSSION . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
AUTHORS’ CONCLUSIONS . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
ACKNOWLEDGEMENTS................................
REFERENCES . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
CHARACTERISTICS OF STUDIES . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
DATA AND ANALYSES . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
Analysis 1.1. Comparison 1 3% saline versus 0.9% saline, Outcome 1 Length of hospital stay (days). . . . . . .Analysis 1.2. Comparison 1 3% saline versus 0.9% saline, Outcome 2 Clinical severity score (post-treatment) at day 1.
Analysis 1.3. Comparison 1 3% saline versus 0.9% saline, Outcome 3 Clinical severity score (post-treatment) at day 2.
Analysis 1.4. Comparison 1 3% saline versus 0.9% saline, Outcome 4 Clinical severity score (post-treatment) at day 3.
Analysis 1.5. Comparison 1 3% salineversus 0.9% saline, Outcome 5 Rate of hospitalization. . . . . . . . .
Analysis 1.6. Comparison 1 3% saline versus 0.9% saline, Outcome 6 Rate of readmission. . . . . . . . . .
APPENDICES . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
WHAT’S NEW . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
HISTORY . . . . . . . . . . . . . . . . . . . . . . .. . . . . . . . . . . . . . . .
CONTRIBUTIONS OF AUTHORS . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
DECLARATIONS OF INTEREST . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
SOURCES OF SUPPORT . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
DIFFERENCES BETWEEN PROTOCOL AND REVIEW . . . . . . . . . . . . . . . . . . . . .
NOTES . . . . . . . . . . .. . . . . . . . . . . . . . . . . . . . . . . . . . . . .
INDEX TERMS
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Nebulized hypertonic saline solution for acute bronchiolitis in infants (Review)
Copyright © 2011 The Cochrane Collaboration. Published by John Wiley & Sons, Ltd.

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[Intervention Review]

Nebulized hypertonic saline solution for acute bronchiolitis in
infants
Linjie Zhang1 , Raúl A Mendoza-Sassi2 , Claire Wainwright3 , Terry P Klassen4
1 Faculty of Medicine, Federal University of Rio Grande, Rio Grande, RS, Brazil. 2 Department of Internal Medicine, Federal University
of Rio Grande, Rio Grande, RS, Brazil. 3 Department of Respiratory...