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CASO CLINICO
Bioquimica Medica
Dra. Nidia Angelica Mota Avalos
MENOPAUSIA
A 52-year-old female presents to your office with complaints of hot flushes, mood swings, irritability, and vaginaldryness and itching. Her last menstrual
period was a little over a year ago. She denies any vaginal discharge. The patient is concerned about having thyroid problems because her friend has
similarsymptoms and was diagnosed with yperthyroidism. On examination, the patient is in no acute distress with normal vital signs. Her physical is normal other than thin, atrophic vaginal mucosa. Athyroid-stimulating hormone (TSH) level is drawn and is normal. The follicle-stimulating hormone (FSH) level is drawn and is markedly elevated.

Responder brevemente:

What is the organ that secretes thefollicle-stimulating hormone (FSH)?

What is the signal that stimulates the release of FSH?

Explicar brevemente:

1. Hormones that control reproduction.
2. Regulation of the normal menstrualcycle.
3. Understand the hormone changes during menopause.

Definir los siguientes conceptos:

Apoptosis/ Estradiol/ FSH/GnRH/ LH/ Progesterone
1. An obese 57-year-old woman did not yet exhibitsymptoms of menopause but was diagnosed with polycystic ovary syndrome (PCOS) and insulin resistance. Her plasma levels of testosterone were above normal. Which one of the following is most likely inthis case?
A. Hyperinsulinemia leading to androgen overproduction by the ovary and its conversion to estrogen in fat cells
B. Androgen overproduction by the adrenal gland and its conversion toestrogen in fat cells
C. Progesterone overproduction by the polycystic ovary leading to its conversion to estrogen
D. LH/FSH ratio = 1
E. Estrogen overproduction by the ovary and conversion totestosterone
2. Which one of the following changes is most likely to be observed in a postmenopausal woman who is not taking hormone supplementation?
A. Cessation of androgen secretion
B. Increased...