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Lymphoma |

Hodgkin’s diseaseNon-Hodgkin’s lymphoma
Indolent lymphoma
Mantle cell lymphoma
Aggressive lymphoma
Highly aggressive lymphoma

PrimaryCNS lymphoma Hodgkin’s diseaseABVD
Doxorubicin (Adriamycin) 25 mg/m2 iv d1 and 15
Bleomycin 10 U/m2 iv d1 and 15
Vinblastine 6 mg/m2 iv d1 and 15Dacarbazine (DTIC) 375 mg/m2 iv d1 and 15
Q4wGianni AM et al. Comparable 3-year outcome following ABVD or BEACOPP first-line chemotherapy, plus pre-planned high-dosesalvage, in advanced Hodgkin's lymphoma (HL): a randomized trial of the Michelangelo, GITIL and IIL cooperative groups. 2008 ASCO annual meeting. Abstract 8506(link to the abstract).    Engert A et al. Two cycles of doxorubicin, bleomycin, vinblastine, and dacarbazine plus extended-field radiotherapy is superior toradiotherapy alone in early favorable Hodgkin's lymphoma: Final results of the GHSG HD7 trial. J Clin Oncol 2007; 25:3495 (link to the article).    Bonadonna Get al. ABVD plus subtotal nodal versus involved-field radiotherapy in early-stage Hodgkin's disease: long-term results. J Clin Oncol 2004; 22:2835 (link to thearticle).  Carde, P et al. Clinical staging versus laparotomy and combined modality with MOPP versus ABVD in early-stage Hodgkin's disease: The H6 twinrandomized trials from the European Organization for Research and Treatment of Cancer Lymphoma Cooperative Group. J Clin Oncol 1993; 11:2258 (link to thearticle).Canellos GP et al. Chemotherapy of advanced Hodgkin’s disease with MOPP, ABVD, or MOPP alternating with ABVD. N Eng J Med 1992; 327:1478 (link to the article). |
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