Stroke 2010

ISSN: 1524-4628
Copyright © 2011 American Heart Association. All rights reserved. Print ISSN: 0039-2499. Online
Stroke is published by the American Heart Association. 7272 Greenville Avenue, Dallas, TX 72514
DOI: 10.1161/STR.0b013e3181f7d043
Stroke 2011;42;227-276; originally published online Oct 21, 2010;
Care and Outcomes Research
Nursing, Council on Clinical Cardiology, andInterdisciplinary Council on Quality of
behalf of the American Heart Association Stroke Council, Council on Cardiovascular
H. Schwamm, Sylvia Wassertheil-Smoller, Tanya N. Turan, Deidre Wentworth and on
Kernan, Pamela H. Mitchell, Bruce Ovbiagele, Yuko Y. Palesch, Ralph L. Sacco, Lee
Susan C. Fagan, Jonathan L. Halperin, S. Claiborne Johnston, Irene Katzan, Walter N.
Karen L. Furie, Scott E. Kasner,Robert J. Adams, Gregory W. Albers, Ruth L. Bush,
Heart Association/American Stroke Association
Ischemic Attack: A Guideline for Healthcare Professionals From the American
Guidelines for the Prevention of Stroke in Patients With Stroke or Transient
http://stroke.ahajournals.org/cgi/content/full/42/1/227
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AHA/ASA Guideline
Guidelines for the Prevention of Stroke in Patients With
Stroke or Transient Ischemic Attack
A Guideline for Healthcare Professionals From the American Heart
Association/American Stroke Association
The American Academy of Neurology affirms thevalue of this guideline as an educational
tool for neurologists.
The American Association of Neurological Surgeons and Congress of Neurological Surgeons
have reviewed this document and affirm its educational content.
Karen L. Furie, MD, MPH, FAHA, Chair; Scott E. Kasner, MD, MSCE, FAHA, Vice Chair;
Robert J. Adams, MD, MS, FAHA; Gregory W. Albers, MD; Ruth L. Bush, MD, MPH;
Susan C. Fagan,PharmD, FAHA; Jonathan L. Halperin, MD, FAHA; S. Claiborne Johnston, MD, PhD;
Irene Katzan, MD, MS, FAHA; Walter N. Kernan, MD;
Pamela H. Mitchell, PhD, CNRN, RN, FAAN, FAHA; Bruce Ovbiagele, MD, MS, FAHA;
Yuko Y. Palesch, PhD; Ralph L. Sacco, MD, MS, FAHA, FAAN; Lee H. Schwamm, MD, FAHA;
Sylvia Wassertheil-Smoller, MD, PhD, FAHA; Tanya N. Turan, MD, FAHA;
Deidre Wentworth, MSN, RN; onbehalf of the American Heart Association Stroke Council, Council
on Cardiovascular Nursing, Council on Clinical Cardiology, and Interdisciplinary Council on Quality of
Care and Outcomes Research
Abstract—The aim of this updated statement is to provide comprehensive and timely evidence-based recommendations on
the prevention of ischemic stroke among survivors of ischemic stroke or transientischemic attack. Evidence-based
recommendations are included for the control of risk factors, interventional approaches for atherosclerotic disease,
antithrombotic treatments for cardioembolism, and the use of antiplatelet agents for noncardioembolic stroke. Further
recommendations are provided for the prevention of recurrent stroke in a variety of other specific circumstances,
including arterialdissections; patent foramen ovale; hyperhomocysteinemia; hypercoagulable states; sickle cell disease;
cerebral venous sinus thrombosis; stroke among women, particularly with regard to pregnancy and the use of
postmenopausal hormones; the use of anticoagulation after cerebral hemorrhage; and special approaches to the
implementation of guidelines and their use in high-risk populations. (Stroke....