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Arch Med Vet 46, 69-74 (2014)
ARTICULO ORIGINAL

Evaluación de la eficacia y persistencia de la moxidectina (10%) e ivermectina (3,15%)
contra infecciones naturales de nematodos gastrointestinales en bovinos del trópico
mexicano
Evaluation of the efficacy and persistence of moxidectin (10%) and ivermectin (3.15%) against
natural infestation of gastrointestinal nematodes in cattle from the Mexicantropics
RI Rodríguez-Vivas*, CG Castillo-Chab, JA Rosado-Aguilar, MM Ojeda-Chi
Departamento de Salud Animal y Medicina Preventiva, Facultad de Medicina Veterinaria y Zootecnia,
Universidad Autónoma de Yucatán, Yucatán, México.
SUMMARY
The efficacy and persistence of ivermectin-3.15% (IVM-3.15%) and moxidectin-10% (MOX-10%) against natural infections of gastrointestinal
nematodes (GIN) in cattlein the Mexican tropics were evaluated. Thirty-three heifers were divided into three groups of 11 animals each, receiving the
following treatments: group one treated with IVM-3.15% (0.63 mg/kg bw) subcutaneously, group two was treated with MOX-10% (1.0 mg/kg bw)
subcutaneously, and group three was the untreated control group. The egg counts per gram of feces were determined by McMaster test on days0, 3, 7,
14, 35, 56, 63, 70, 77, 84, 91 and 98 post-treatment (PT). Also, larval cultures were performed to identifying L3 nematodes from the strongylida order by
the Corticelli-Lai technique. IVM-3.15% and MOX-10% had similar efficacy (P < 0.001) from day 3 to 70 PT (100-75.7% and 100-93.1% respectively).
MOX-10% showed greater persistence than IVM-3.15% at day 77 PT. The identified genera ofnematodes from the strongylida order were Cooperia,
Oesophagostomun, Ostertagia, Haemonchus and Trichostrongylus, the latter two being the most frequent. We conclude that IVM-3.15% and MOX-10%
have good efficacy for controlling natural infections of GIN up to day 70 PT, and MOX-10% have greater persistence compared to IVM-3.15%, although
its effectiveness was low at day 77 PT (40.8%). It is concludedthat IVM-3.15% and MOX-10% subcutaneously have a good efficacy for controlling
natural infections of GIN of the strongylida order. It was observed that MOX-10% have greater persistence than IVM-3.15% (93.1% and 75.7% of efficacy
at 70 days PT, respectively), probably associated with the higher dose of MOX applied (1.6 times).
Key words: moxidectin 10%, ivermectin 3.15%, efficacy, persistence.RESUMEN
Se evaluó la eficacia y persistencia de ivermectina-3,15% (IVM-3,15%) y moxidectina-10% (MOX-10%) contra infecciones naturales de nematodos
gastrointestinales (NGI) en bovinos del trópico mexicano. Se utilizaron 33 bovinos hembras que fueron divididos en tres grupos de 11 animales
recibiendo los siguientes tratamientos: grupo uno tratado con IVM-3,15% (0,63 mg/kg de pv) vía subcutánea, grupodos tratado con MOX-10% (1,0 mg/
kg de pv) vía subcutánea, y grupo tres sin tratamiento (control). El conteo de huevos por gramo de heces se determinó mediante las pruebas McMaster
los días 0, 3, 7, 14, 35, 56, 63, 70, 77, 84, 91 y 98 postratamiento (PT). Asimismo, se realizaron coprocultivos de larvas L3 para la identificación de
nematodos del orden strongylida mediante la técnica deCorticelli-Lai. La IVM-3,15% y MOX-10% presentaron eficacias similares (P > 0.001) del
día 3 al 70 PT (100-75,7% y 100-93,1% respectivamente). La MOX-10% presentó mayor persistencia que la IVM-3,15% al día 77 PT. Los géneros de
nematodos del orden strongylida identificados fueron Cooperia, Oesophagostomun, Ostertagia, Haemonchus y Trichostrongylus, siendo los dos últimos
los más frecuentes. Se concluye quela IVM-3,15% y MOX-10% vía subcutánea presentan buena eficacia para el control de infecciones naturales de
NGI del orden strongylida. Se observó que la MOX-10% presenta mayor persistencia que la IVM-3,15% (eficacia de 93,1% y 75,7% a los 70 días PT,
respectivamente), probablemente asociado a la mayor dosis de MOX aplicada (1,6 veces).
Palabras clave: moxidectina 10%, ivermectina 3,15%, eficacia,...