Fracturas Vertebrales
Páginas: 2 (307 palabras)
Publicado: 27 de abril de 2012
Rev Méd Chile 2007; 135: 31-36
Fracturas vertebrales, osteoporosis y vitamina D en la posmenopausia. Estudio en 555 mujeres en Chile
José A Rodríguez P1,2,3, Gonzalo Valdivia C4,Patricio Trincado M3.
Vertebral fractures, osteoporosis and vitamin D levels in Chilean postmenopausal women
Background: Approximately one-third of vertebral fractures can be clinicallydiagnosed. Aim: To study the frequency of vertebral fractures in postmenopausal women. Patients and methods: We recruited 555 postmenopausal women from Santiago, Chile, aged 5584 years, whomanifested interest in their bone health. All were healthy by self-declaration and by general clinical and laboratory tests and had not taken any bone-active therapy. They all underwent a spineand femoral neck (FN) densitometry and a digital lateral spine X-ray from T4 to L4 was obtained. PTH, calcidiol, and other parameters of calcium metabolism were also measured. Results:Overall, 142 of 478 patients with a complete study (29.7%) had at least one vertebral fracture. The proportion of women with fractures increased with age. A T score below -2.5 in the spine and hipwas found in 32% and 14% of women, respectively. The proportion of women with spinal opeoporosis doubled between ages 55-70 and remained constant afterwards. In contrast, at the femoralneck, this proportion increased progressively reaching 53.3% at age 80-85. However, 56% of patients with vertebral fractures did not have densitometric osteoporosis in any location. Calcidiollevels were 16.8±6.8 ng/mL. With a cutoff point of 17 ng/mL, 47.5% of the patients had hypovitaminosis D. There was no association between calcidiol levels and vertebral fractures or bonedensity at the spine or femoral neck. Patients with fractures differed from those without fractures in that they had significantly lower bone density at the spine and hip and were older (p
Fracturas vertebrales, osteoporosis y vitamina D en la posmenopausia. Estudio en 555 mujeres en Chile
José A Rodríguez P1,2,3, Gonzalo Valdivia C4,Patricio Trincado M3.
Vertebral fractures, osteoporosis and vitamin D levels in Chilean postmenopausal women
Background: Approximately one-third of vertebral fractures can be clinicallydiagnosed. Aim: To study the frequency of vertebral fractures in postmenopausal women. Patients and methods: We recruited 555 postmenopausal women from Santiago, Chile, aged 5584 years, whomanifested interest in their bone health. All were healthy by self-declaration and by general clinical and laboratory tests and had not taken any bone-active therapy. They all underwent a spineand femoral neck (FN) densitometry and a digital lateral spine X-ray from T4 to L4 was obtained. PTH, calcidiol, and other parameters of calcium metabolism were also measured. Results:Overall, 142 of 478 patients with a complete study (29.7%) had at least one vertebral fracture. The proportion of women with fractures increased with age. A T score below -2.5 in the spine and hipwas found in 32% and 14% of women, respectively. The proportion of women with spinal opeoporosis doubled between ages 55-70 and remained constant afterwards. In contrast, at the femoralneck, this proportion increased progressively reaching 53.3% at age 80-85. However, 56% of patients with vertebral fractures did not have densitometric osteoporosis in any location. Calcidiollevels were 16.8±6.8 ng/mL. With a cutoff point of 17 ng/mL, 47.5% of the patients had hypovitaminosis D. There was no association between calcidiol levels and vertebral fractures or bonedensity at the spine or femoral neck. Patients with fractures differed from those without fractures in that they had significantly lower bone density at the spine and hip and were older (p
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