Inmunologia

Immunology 26Mar2009
1 – Basic Concepts and Components of the Immune System
1.1) The ____ immune system uses ____ as well as molecules (e.g. complement
components). The ____ immune system uses ____ as well as antigen recognition
molecules.
a) Adaptive; Phagocytes; Innate; Lymphocytes
b) Adaptive; Lymphocytes; Innate; Phagocytes
c) Innate; Phagocytes; Adaptive; Lymphocytes
d) Innate;Lymphocytes; Adaptive; Phagocytes

1.2) Phagocytic white cells (leukocytes, e.g. macrophages) congregate within ____ whenforeign organisms get through a cut in the skin.
a) Microseconds
b) Seconds
c) Minutes
d) Hours
e) Days

1.3) Which of the following mediates an early response to viral infections by the innateimmune system?
a) Complement components
b) Vaccines
c) T and B lymphocytes
d)Cytokines
e) Interferons

1.4) Which of the following is a messenger that mediates the connection between the
innate and adaptive immune systems?
a) Complement components
b) Vaccines
c) T and B lymphocytes
d) Cytokines
e) Interferons

1.5) Which of the following immune system components would NOT recognize a
macromolecule epitope (binding site)?
a) Phagocyte
b) T lymphocyte
c) Blymphocyte
d) Antibody

1.6) Which of the following is a large genomic region or gene family found in most
vertebrates, playing an important role in immunity?
a) Antigen-recognition molecules
b) Major histocompatibility complexes (MHCs)
c) Human leukocyte antigens (HLAs)
d) Immunoglobulin
e) Epitopes

1.7) B-cell antigen receptors can interact directly with antigen, whereas T-cell antigenreceptors only recognize antigen when it is presented to them on the surface of another
cell.
a) True
b) False

1.8) How are B-cell and T-cell antigen receptors distributed?
a) By size (steric hindrance)
b) By molecular weight
c) By activation (clonal)
d) By location in the body
e) Equally (same number of each receptor)

1.9) A medical student acquired hepatitis B through aneedle-stick injury. The student
had not received their vaccinations for this virus and eventually experienced liver
problems. One of the clinical signs of this disease is jaundice, which turns the skin and
sclera what color?
a) Black
b) Red
c) White
d) Yellow
e) Blue

1.10) Monoclonal antibodies (mAb) are antibodies with a wide range of clinically
important applications, such as pregnancy tests,cancer diagnosis, and cancer treatment.
These antibodies are ____ and come from ____ parent cell(s).
a) Dissimilar; Multiple
b) Dissimilar; A single
c) Identical; Multiple
d) Identical; A single

1.11) Adaptive immune system response typically takes how long/
a) Microseconds
b) Seconds
c) Minutes
d) Hours
e) Days

2 – Basic Concepts
1) Which of the following is NOT true whencomparing innate to adaptive immunity?
a) Innate responds quickly and adaptive responds slowly
b) Innate has few pathogen (non-self) recognition mechanisms and adaptive has
many
c) Innate has immunologic memory and adaptive does not
d) Innate does not show response improvements over time and adaptive does
e) Innate response is non-specific and adaptive is very specific

2) Phagocytes ingestparticular matter into cells for degradation. Which of the following
is NOT considered a phagocyte?
a) Macrophage
b) Neutrophil
c) Eosinophil
d) Basophil
e) Lymphocyte

3.1) Which of the following components of the innate immune system involves
recognition molecules such as mannan-binding lectin (MBL) for bacteria with mannose
on the surface?
a) Natural killer (NK) cells
b) Complementsystem
c) Oxygen dependent and independent killing
d) Interferons
e) Acute phase proteins

3.2) Which of the following components of the innate immune system involves cytokines
produced by macrophages, which are produced during infection?
a) Natural killer (NK) cells
b) Complement system
c) Oxygen dependent and independent killing
d) Interferons
e) Acute phase proteins

3.3) Which of...