Predictive fac liver transplantation for polycystic liver with massive

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World J Gastroenterol 2009 October 28; 15(40): 5112-5113 World Journal of Gastroenterology ISSN 1007-9327
© 2009 The WJG Press and Baishideng. All rights reserved.

CASE REPORT

Liver transplantation for polycystic liver with massive hepatomegaly: A case report

Wei-Wei Jiang, Feng Zhang, Li-Yong Pu, Xue-Hao Wang,Lian-Bao Kong
Wei-Wei Jiang, Department of Neonatal Surgery, Nanjing Children’s Hospital Affiliated to Nanjing Medical University, 72 Guangzhou Road, Nanjing 210008, Jiangsu Province, China Feng Zhang, Li-Yong Pu, Xue-Hao Wang, Lian-Bao Kong, Department of Liver Transplantation Center, The First Affiliated Hospital of Nanjing Medical University, The National Institute of Living Donor LiverTransplantation, 300 Guangzhou Road, Nanjing 210029, Jiangsu Province, China Author contributions: Jiang WW and Kong LB contributed equally to this work; Jiang WW, Pu LY, Kong LB perfomed clinical examinations; Jiang WW, Zhang F, Pu LY, Wang XH, Kong LB were in charge of surgery; Jiang WW wrote the paper. Supported by A grant from Jiangsu Health Department of China, No. RC2007058 Correspondence to:Lian-Bao Kong, PhD, MD, Department of Liver Transplantation Center, The First Affiliated Hospital of Nanjing Medical University, The National Institute of Living Donor Liver Transplantation, 300 Guangzhou Road, Nanjing 210029, Jiangsu Province, China. lbkong@njmu.edu.cn Telephone: +86-25-83718836-6746 Fax: +86-25-83672106 Received: July 11, 2009 Revised: September 7, 2009 Accepted: September 14, 2009Published online: October 28, 2009

Peer reviewer: Dr. Shoji Kubo, Department of Hepato-BilliaryPancreatic Surgery, Osaka City University Graduate School of Medicine, Osaka, 545-8585, Japan

Jiang WW, Zhang F, Pu LY, Wang XH, Kong LB. Liver transplantation for polycystic liver with massive hepatomegaly: A case report. World J Gastroenterol 2009; 15(40): 5112-5113 Available from: URL:http://www.wjgnet.com/1007-9327/15/ 5112.asp DOI: http://dx.doi.org/10.3748/wjg.15.5112

INTRODUCTION
A previous study has shown that liver or combined liver-kidney transplantation can be a valuable surgical technique for the treatment of polycystic liver disease[1]. Here, we present the case of a 35-year-old woman with polycystic liver disease, who underwent orthotopic liver transplantation (OLT) onNovember 11, 2008.

CASE REPORT Abstract
A previous study has shown that liver or combined liver-kidney transplantation can be a valuable surgical technique for the treatment of polycystic liver disease. Herein, we present the case of a 35-year-old woman with polycystic liver disease, who underwent orthotopic liver transplantation (OLT) on November 11, 2008. The whole-size graft was taken from adeceased donor (a 51-year-old man who died of a heart attack). Resection in a patient with massive hepatomegaly is very difficult. Thus, after intercepting the portal hepatic vein, left hepatectomy was performed, then the vena cava was intercepted, the second and third porta hepatic isolated, and finally, right hepatectomy was performed. OLT was performed successfully. The recipient did wellafter transplantation. This case suggested that OLT is an effective therapeutic option for polycystic liver disease and left hepatectomy can be performed first during OLT if the liver is over enlarged.
© 2009 The WJG Press and Baishideng. All rights reserved.

Key words: Hepatectomy; Liver transplantation; Polycystic liver

I n O c t o b e r 2 0 0 8 , a 3 5 - y e a r- o l d wo m a n w i t h abody weight of 52 kg was admitted to the Liver Transplantation Center, the First Affiliated Hospital of Nanjing Medical University to underg o liver transplantation. This patient had a significant family history of polycystic disease, and her mother had died of dyscrasia that resulted from polycystic liver and kidney diseases. She had normal liver function [alanine aminotransferase (ALT) 35.7 U/L,...