There are two methods for treating depression, pharmacological and psychological.
The discovery of antidepressant drugs around the decade of the 40 has been one of the most importantadvances in the fight to alleviate the symptoms of mental disorder.
There are four different types of drugs used to treat depression: monoamine oxidase inhibitors, tricyclic antidepressants,selective inhibitors of monoamine reuptake and lithium.
The iproniacida is a monoamine oxidase inhibitor. It was initially used to treat tuberculosis,did not achieve any success in the treatment of this,however, was that patients felt relief ondepression caused by their disease. After testing in depressed patients concluded that it was effective to alleviate symptoms of depression.
Side effectsmay occur as the so-called cheese effect: foods containing tyramine (egcheese) cause blood pressure to rise dangerously together this drug and can cause strokes.
Imipramine was the first tricyclicantidepressant. A priori it was thought that would be effective as an antipsychotic, later studies showed that it worked better as an antidepressant and is also safer than the use of inhibitors (MAO).Tricyclic antidepressantsprevent the norepinephrine and serotonin are captured so that its level increases in the brain.
John Cade, a psychiatrist based in Australia, studied the effects of lithiumin the guinea pigfirst and then in humans with positive results. Lithium is effective in treating depression and to treat mania in patients with bipolar disorder, acts as a mood stabilizer. What itdoes isslow down the transition between depression and mania, depression is not itself. Until the discovery of other mood stabilizers also treat depression, lithium was the standard treatment forpatients with bipolar affective disorder.
Selective inhibitors of monoamine reuptake inhibitors (SSRIs) were discovered in the late80's still best known as Prozak. Fluoxetine is what contains the drug, it...
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