Estres Oxidativo

Páginas: 2 (376 palabras) Publicado: 24 de enero de 2013
Oxidative stress is caused by an imbalance between the production of reactive oxygen and a biological system's ability to readily detoxify the reactive intermediates or easily repair the resultingdamage.
in the normal redox (reduction oxidation) state of cells can cause toxic effects through the production of peroxides and free radicals that damage all components of the cell, includingproteins, lipids, and DNA. Further, some reactive oxidative species act as cellular messengers in redox signaling. Thus, oxidative stress can cause disruptions in normal mechanisms of cellular signaling.oxidative stress is thought to be involved in the development of many diseases or may exacerbate their symptoms. These include cancer,[1] Parkinson's disease, Alzheimer's disease,[2] atherosclerosis,heart failure,[3] myocardial infarction,[4] Schizophrenia;[5] Bipolar disorder,[6] fragile X syndrome,[7] Sickle Cell Disease,[8] and chronic fatigue syndrome.[9] However, reactive oxygen species canbe beneficial, as they are used by the immune system as a way to attack and kill pathogens.[10] Short-term oxidative stress may also be important in prevention of aging

An antioxidant is a moleculethat inhibits the oxidation of other molecules.
The more important are GSH (glutation) Although oxidation reactions are crucial for life, they can also be damaging; plants and animals maintaincomplex systems of multiple types of antioxidants, such as glutathione, vitamin C, and vitamin E as well as enzymes such as catalase, superoxide dismutase and various peroxidases. Low levels ofantioxidants, or inhibition of the antioxidant enzymes, cause oxidative stress and may damage or kill cells
Ascorbic acid or "vitamin C" c as a reducing agent to reverse oxidation in liquids. When there are morefree radicals (reactive oxygen species, ROS) in the human body than antioxidants, the condition is called oxidative stress,[61] and has an impact on cardiovascular disease, hypertension, chronic...
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