Huntingtons Disease

Huntington Disease Pedigree
Huntington Disease is a genetic disorder that will affect the muscle coordination and will lead to cognitive decline and psychiatric problems. The disease occurs in midadult life. This disease is caused by an autosomal dominant mutation, which means a person either has two copies of Huntington disease. In a punnett square there is a 50% possibility that the childof an infected person will have Huntington disease. Huntington disease can begin at any age. Its frequent in between years 35 and 44 of age.
The early symptoms is small changes in mood. Lack ofcoordination and unsteady movements. As it gets stronger there are more bodily jerks and mental and behavior issues. Physical damage from frequent falls in later stages. There is no cure for Huntingtondisease, but there is full time care that should be required in the later stages in of the disease. The treatments consist of physical therapy that relieves many symptoms of Huntington disease.
Inthe Huntington disease pedigree provided. In the P generation there is a infected female with her alleles as Hh, and a non infected male with his alleles hh. There offspring shows a infected femalewith Hh, an infected male with Hh, and a non infected male with hh. The circled individual is not infected at all, which means his children will not have Huntington disease unless is paired with anotherinfected individual. He paired with a non infected female and their offspring is a male and a female that does not have Huntington disease. The infected male is paired with a non infected female andtheir offspring is a infected male. Lastly the infected female with Hh genotype is paired with a non infected male and their offspring is a non infected male with a genotype of hh, and a infectedfemale with a genotype of Hh.
People in the pedigree might seek a genetic counselor to show the probability of their offspring. In the pedigree there will always be some inheritance of Huntington...