Licenciada

HARRISON'S
INTERNAL
MEDICINE
SELF-ASSESSMENT
AND BOARD REVIEW

Editorial Board

ANTHONY S. FAUCI,

MD
Chief, Laboratory of Immunoregulation
Director, National Institute of Allergy and Infectious Diseases
National Institutes of Health
Bethesda

EUGENE BRAUNWALD, MD
Distinguished Hersey Professor of Medicine
Harvard Medical School
Chairman, TIMI Study Group, Brigham and Women’sHospital
Boston
DENNIS L. KASPER,

MD
William Ellery Channing Professor of Medicine
Professor of Microbiology and Molecular Genetics
Harvard Medical School
Director, Channing Laboratory
Department of Medicine
Brigham and Women’s Hospital
Boston

STEPHEN L. HAUSER,

MD
Robert A. Fishman Distinguished Professor and
Chairman, Department of Neurology
University of California, SanFrancisco
San Francisco

DAN L. LONGO, MD
Scientific Director, National Institute on Aging
National Institutes of Health
Bethesda and Baltimore, Maryland
J. LARRY JAMESON,

M D , P hD
Professor of Medicine
Vice-President for Medical Affairs and Lewis Landsberg Dean
Northwestern University Feinberg School of Medicine
Chicago

JOSEPH LOSCALZO, MD, PhD
Hersey Professor of the Theory andPractice of Medicine
Harvard Medical School
Chairman, Department of Medicine
Physician-in-Chief, Brigham and Women’s Hospital
Boston

HARRISON'S
INTERNAL
MEDICINE
SELF-ASSESSMENT
AND BOARD REVIEW
For use with the 17th edition of HARRISON’S PRINCIPLES OF INTERNAL MEDICINE

EDITED BY
CHARLES WIENER, MD
Professor of Medicine and Physiology
Vice Chair, Department of MedicineDirector, Osler Medical Training Program
The Johns Hopkins University School of Medicine
Baltimore

Contributing Editors
Gerald Bloomfield, MD, MPH
Cynthia D. Brown, MD
Joshua Schiffer, MD
Adam Spivak, MD
Department of Internal Medicine
The Johns Hopkins University School of Medicine
Baltimore

New York Chicago San Francisco Lisbon London Madrid Mexico City
New Delhi San Juan Seoul SingaporeSydney Toronto

Copyright © 2008, 2005, 2001, 1998, 1994, 1991, 1987 by The McGraw-Hill Companies, Inc. All rights reserved. Manufactured in the United States of
America. Except as permitted under the United States Copyright Act of 1976, no part of this publication may be reproduced or distributed in any form or by
any means, or stored in a database or retrieval system, without the priorwritten permission of the publisher.
0-07-164131-9
The material in this eBook also appears in the print version of this title: 0-07-149619-X.
All trademarks are trademarks of their respective owners. Rather than put a trademark symbol after every occurrence of a trademarked name, we use names
in an editorial fashion only, and to the benefit of the trademark owner, with no intention of infringementof the trademark. Where such designations appear
in this book, they have been printed with initial caps.
McGraw-Hill eBooks are available at special quantity discounts to use as premiums and sales promotions, or for use in corporate training programs. For more
information, please contact George Hoare, Special Sales, at george_hoare@mcgraw-hill.com or (212) 904-4069.
TERMS OF USE
This is acopyrighted work and The McGraw-Hill Companies, Inc. (“McGraw-Hill”) and its licensors reserve all rights in and to the work. Use of this work
is subject to these terms. Except as permitted under the Copyright Act of 1976 and the right to store and retrieve one copy of the work, you may not decompile, disassemble, reverse engineer, reproduce, modify, create derivative works based upon, transmit,distribute, disseminate, sell, publish or sublicense the
work or any part of it without McGraw-Hill’s prior consent. You may use the work for your own noncommercial and personal use; any other use of the work
is strictly prohibited. Your right to use the work may be terminated if you fail to comply with these terms.
THE WORK IS PROVIDED “AS IS.” McGRAW-HILL AND ITS LICENSORS MAKE NO GUARANTEES...