Respuesta metabolica al trauma

Metabolic response to trauma and surgery

One of the most important biological responses in mammals and especially in humans is the phenomenon of response to aggression and trauma.
Aneuroendocrine response occurs in the body, with the release of a large amount of chemicals and hormones, whose effect is to mobilize energy substrates to maintain the oxygen supply in order to maintain theirfunction in emergency conditions by a profound alteration in the body's metabolic functions.
In essence, these functions involve a high protein catabolism that accompanies the increase of energyconsumption to the body with a large mass loss when excessive cell that can lead to multisystem failure and death.
neuroendocrine
When homeostasis is altered by any changes in circulating fluids, thermalimbalance, basic acid alterations, pain, infection, trauma or any problem in providing a partially awakens substrates at rest, through the receivers which causes a series neuroendocrine physiologicalreactions that preserve the passage of fluids to critical organs and provision of substrates and oxygen to cells critically dependent on them, to preserve the integrity of the organism in the acutephase and preparing for Cannon's

POST-TRAUMATIC CHANGES
uthbertson phases divided in three post-traumatic
EBB-phase or shock, which occurs in the first few hours and is characterized byhyperglycemia and conservation state volume.
FLOW-or catabolic phase, accompanied by a negative nitrogen balance, heat and severe catabolism.
-Anabolic phase or repair tissue. last month
Carbohydratemetabolism is altered to maintain glucose available to the blood cells, kidney, and brain tissue begins to heal wounded. Glucose reserves are limited and therefore must be replaced when exhaustedgluconeogenesis from lactate and amino acids. There is then an increase in blood glucose. the Iípjdos, meanwhile, energy source liver, kidney, heart and muscle, and stored as triglicéridos.se catabolized to...