FIVE BATCH ANALYSIS
A. Castro A., Ph. C.
J. Díaz T., Ph. C.
PROFICOL ANDINA B.V. SUCURSAL COLOMBIA
Quality Control Laboratory
Barranquilla - Colombia
The purpose of this study was to verify the chemical composition of Propanil Technical manufactured atPROFICOL ANDINA B.V. SUCURSAL COLOMBIA and to provide updated chromatograms for Propanil, 3,4 - Dichloroaniline and 3, 3´, 4, 4´- Tetrachloroazobenzene (TCAB).
This study is based on the Report No. 01 – 01, “Propanil Technical – Five lots Analysis and method validation performed by AGAN Chemical Manufacturers, Ltd” in March, 2001.
Study Director: Alejandro de CastroA.
Analysts: José Díaz T. Ph. C.
Jorge Yaber Ph. C.
DATE OF COMPLETION: August 9, 2004
II. MATERIALS AND METHODS
Five lots of Propanil Technical manufactured at PROFICOL ANDINA B.V. SUCURSAL COLOMBIA.
|BATCH No. |DATE OF MANUFACTURING |
| | |
| | |
|PP04040162 |April/2004 |
|PP04050200 |May/2004 |
| | |
| | |
|PP04070322 |July/2004 |
N – (3,4-Dichlorophenyl)propionamide (CAS)
3´, 4´- Dichloropropionanilide (IUPAC)
3, 4- Dichloroaniline (DCA)
3, 3´, 4 , 4´- Tetrachloroazobenzene (IUPAC)
The determination of Propanil in Propanil Technical was done by GC equipped with FID detector, using Benzil Benzoate (BB) 1 % in Acetone as Internal Standard.Sample and standard solutions were prepared similarly: Propanil standard (30 mg) and 2 mL solution BB (1 % in Acetone) were dissolved in 25 mL Methanol RG.
1. GC system: Hewlett Packard 4890 – 5890 series II, equipped with detector FID and FPD.
2. Column: HP-17 50 % Phenyl Metil Siloxane.
3. Analytical Balance: Mettler AE-200
4. PC Dell and Software ASTERIK.
Reactive1. Methanol RG
3. Propanil Std. Analytical (98.6 %)
4. Propanil Technical (98.5 %)
5. Benzil Benzoate (BB) Internal Std. (99%)
6. Solution Benzil Benzoate (BB) Internal Std.1% in Acetone (Sol BB)
Oven temp = 210 ºC
Injector temp = 270 ºC
Detector temp = 300ºC
Flow N2 = 10.0 mL/min
Split = 3.0 mL/min
Purge = 3.0...