Huesos

This article was downloaded by:[Swets Content Distribution] On: 16 April 2008 Access Details: [subscription number 768307933] Publisher: Taylor & Francis Informa Ltd Registered in England and Wales Registered Number: 1072954 Registered office: Mortimer House, 37-41 Mortimer Street, London W1T 3JH, UK

Critical Reviews in Food Science and Nutrition
Publication details, including instructionsfor authors and subscription information: http://www.informaworld.com/smpp/title~content=t713606380

Delay of Natural Bone Loss by Higher Intakes of Specific Minerals and Vitamins

A. Schaafsma a; P. J. F. de Vries a; W. H. M. Saris b a Friesland Coberco Dairy Foods, Dep. of Research & Development Leeuwarden, Leeuwarden, The Netherlands. b University Maastricht, Dept. Human Biology, Maastricht,The Netherland. Online Publication Date: 01 May 2001 To cite this Article: Schaafsma, A., de Vries, P. J. F. and Saris, W. H. M. (2001) 'Delay of Natural Bone Loss by Higher Intakes of Specific Minerals and Vitamins', Critical Reviews in Food Science and Nutrition, 41:3, 225 - 249 To link to this article: DOI: 10.1080/20014091091805 URL: http://dx.doi.org/10.1080/20014091091805

PLEASE SCROLLDOWN FOR ARTICLE Full terms and conditions of use: http://www.informaworld.com/terms-and-conditions-of-access.pdf This article maybe used for research, teaching and private study purposes. Any substantial or systematic reproduction, re-distribution, re-selling, loan or sub-licensing, systematic supply or distribution in any form to anyone is expressly forbidden. The publisher does not give anywarranty express or implied or make any representation that the contents will be complete or accurate or up to date. The accuracy of any instructions, formulae and drug doses should be independently verified with primary sources. The publisher shall not be liable for any loss, actions, claims, proceedings, demand or costs or damages whatsoever or howsoever caused arising directly or indirectly inconnection with or arising out of the use of this material.

Downloaded By: [Swets Content Distribution] At: 15:08 16 April 2008

Critical Reviews in Food Science and Nutrition, 41(3):225–249 (2001)

Delay of Natural Bone Loss by Higher Intakes of Specific Minerals and Vitamins
A. Schaafsma,1* P. J. F. de Vries,1 and W. H. M. Saris2
1 2

Friesland Coberco Dairy Foods, Dep. of Research &Development Leeuwarden, Leeuwarden, The Netherlands; University Maastricht, Dept. Human Biology, Maastricht, The Netherlands
Corresponding author: A. Schaafsma, Friesland Coberco Dairy Foods, Dept. Research and Development, Leeuwarden, P.O. Box 226, 8901 MA Leeuwarden, The Netherlands, fax: +31 58 2992540, e-mail: a.schaafsma@fdf.nl.

*

KEY WORDS: nutrition, bone mineral density, bonemetabolism, postmenopausal women
ABSTRACT: For early prevention or inhibition of postmenopausal and age-related bone loss, nutritional interventions might be a first choice. For some vitamins and minerals an important role in bone metabolism is known or suggested. Calcium and vitamin D support bone mineral density and are basic components in most preventive strategies. Magnesium is involved in a number ofactivities supporting bone strength, preservation, and remodeling. Fluorine and strontium have bone-forming effects. However, high amounts of both elements may reduce bone strength. Boron is especially effective in case of vitamin D, magnesium, and potassium deficiency. Vitamin K is essential for the activation of osteocalcin. Vitamin C is an important stimulus for osteoblast-derived proteins.Increasing the recommended amounts (US RDA 1989), adequate intakes (US DRI 1997), or assumed normal intakes of mentioned food components may lead to a considerable reduction or even prevention of bone loss, especially in late postmenopausal women and the elderly.

I. INTRODUCTION Bone loss at an older age (>50 years) will sooner or later lead to osteoporosis and fractures in millions of people...