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Genetic diseases of the heart are those that are caused by a mutation in one or more genes that affect the structure or function of the heart muscle. Many of these diseases are rare, inherited onlywhen one or both parents pass down the affected gene. Some of these conditions are especially common in certain communities or cultures where the populations are relatively isolated.
Arrhythmogenicright ventricular dysplasia
Arrhythmogenic right ventricular dysplasia is a genetic disease in which normal heart tissue is progressively replaced with fat and scar tissue. According to St.Lukes-Roosevelt Hospital Center, tissue damage occurs predominantly in the right chamber of the heart. People who inherit this genetic disease may develop arrhythmias, or abnormal heart rhythms. Arrhythmogenicright ventricular dysplasia is a known cause of sudden death from cardiac arrest in people younger than 30. The condition is especially prevalent in communities in northeast Italy.
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Brugada Syndrome
Brugada syndrome is a life-threatening, frequently inherited disordercharacterized by an abnormal heart rhythm, called a Brugada sign, according to the Mayo Clinic. This arrhythmia prevents the chambers of the heart from pumping effectively, preventing blood fromtraveling normally throughout the body. As a result, fainting or sudden heart attack leading to death can occur.
Familial Dilated Cardiomyopathy
Dilated cardiomyopathy is a condition in which theheart's left ventricle becomes enlarged and weak, reducing the heart's ability to pump blood. Over time, the disorder can damage multiple organs and lead to congestive heart failure. According to theCleveland Clinic, about one-third of patients with dilated cardiomyopathy have an inherited form called familial dilated cardiomyopathy. Familial dilated cardiomyopathy is autosomal dominant, meaning you...