1. Eukaryotic cells have a true nucleus, bound by a double membrane. Prokaryotic cells have nonucleus. The purpose of the nucleus is to sequester the DNA-related functions of the big eukaryotic cell into a smaller chamber, for the purpose of increased efficiency. This function is unnecessaryfor the prokaryotic cell, because its much smaller size means that all materials within the cell are relatively close together. Of course, prokaryotic cells do have DNA and DNA functions. Biologistsdescribe the central region of the cell as its "nucleoid" (-oid=similar or imitating), because it's pretty much where the DNA is located. But note that the nucleoid is essentially an imaginary"structure." There is no physical boundary enclosing the nucleoid.
2. Eukaryotic DNA is linear; prokaryotic DNA is circular (it has no ends).
3. Eukaryotic DNA is complexed with proteins called "histones,"and is organized into chromosomes; prokaryotic DNA is "naked," meaning that it has no histones associated with it, and it is not formed into chromosomes. Though many are sloppy about it, the term"chromosome" does not technically apply to anything in a prokaryotic cell. A eukaryotic cell contains a number of chromosomes; a prokaryotic cell contains only one circular DNA molecule and a variedassortment of much smaller circlets of DNA called "plasmids." The smaller, simpler prokaryotic cell requires far fewer genes to operate than the eukaryotic cell.
4. Both cell types have many, manyribosomes, but the ribosomes of the eukaryotic cells are larger and more complex than those of the prokaryotic cell. Ribosomes are made out of a special class of RNA molecules (ribosomal RNA, or rRNA) and aspecific collection of different proteins. A eukaryotic ribosome is composed of five kinds of rRNA and about eighty kinds of proteins. Prokaryotic ribosomes are composed of only three kinds of rRNA...